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Updated: Jul 19, 2025

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs
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在黑色素瘤进展中,YAP1控制了N-cadherin介导的瘤-肌瘤相互作用

Yao Xio1, Lilni Zhou1, Thomas Andl

  • 1University of Cincinnati.

Research square
|August 7, 2023
PubMed
概括

癌症相关纤维细胞 (CAFs) 中的Yes相关蛋白1 (YAP1) 通过上调N-cadherin来驱动黑色素瘤的进展. 在CAF中YAP1枯竭通过降低瘤细胞中N-cadherin和PI3K-AKT信号的调节来抑制黑色素瘤的生长.

关键词:
这是一种N-cadherin.是的相关蛋白1 是的相关蛋白1纤维细胞的细胞.黑色素瘤是一种黑色素瘤.微观环境是一个微观环境.

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