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Updated: Jul 19, 2025

Aip1p Dynamics Are Altered by the R256H Mutation in Actin
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Aip1p Dynamics Are Altered by the R256H Mutation in Actin

Published on: July 30, 2014

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F-actin聚合因子的突变抑制了远端关节缩症5型 (DA5) PIEZO2在Caenorhabditis elegans中的致病变体

Xiaofei Bai, Harold E Smith, Luis O Romero

    bioRxiv : the preprint server for biology
    |August 7, 2023
    PubMed
    概括

    研究人员将GEX-3确定为一种PIEZO通道疾病变体的抑制剂. 这一发现突显了细胞骨在PIEZO通道功能中的作用,并提供了有关人类疾病的见解.

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    Quantitative Approaches for Studying Cellular Structures and Organelle Morphology in Caenorhabditis elegans08:47

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    相关概念视频

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    Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. Actin monomers polymerize to form a complex network of polarized filaments, the actin cytoskeleton, that plays a crucial role in many cellular processes, including cell motility, division, endocytosis, and metastasis of cancer cells.
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