相关实验视频

Updated: Jul 19, 2025

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release

Published on: June 12, 2021

气囊-血液相互作用增强了超声波成像对比度

Bill Ling^1,2, Jeong Hoon Ko^1,2, Benjamin Stordy^3,4

¹Division of Chemistry and Chemical Engineering, California Institute of Technology; Pasadena, CA 91125, USA.

bioRxiv : the preprint server for biology

|August 7, 2023

概括

气囊 (GVs) 与红细胞和蛋白质等血液成分相互作用,影响其性能. 修改GV表面可以改善它们在纳米医学和生物医学应用中的使用.

科学领域:

生物医学工程生物医学工程
纳米技术纳米技术
生物物理学的生物物理.

背景情况:

气囊 (GVs) 是蛋白质纳米结构,在超声波,MRI和光学成像/治疗中具有潜力.
了解GV与血液的相互作用对于它们在纳米医学中的系统性使用至关重要.

研究的目的:

为了研究血液中的气体囊泡 (GVs) 的动态.
为了确定血液成分如何影响GV性能和免疫性.
探索表面修饰策略,以增强GV *in vivo* 应用.

主要方法:

超声波和光学成像技术
表面功能化技术的技术.
流细胞计和质谱仪的流量计和质谱仪.

主要成果:

红细胞和血清蛋白与GVs结合,影响它们的声学特性,循环寿命和免疫反应.
GV表面修饰改变了与血液成分的相互作用.
修改后的GV表现出改变的 *in vivo* 性能.

结论:

血液成分相互作用显著影响GV*in vivo*的行为.
表面工程提供了一种可行的策略,以优化GV用于纳米医学.
这项研究为开发GV作为生物医学剂提供了必要的见解.

更多相关视频

Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound

Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound

Published on: March 4, 2015

Real-Time Intravital Multiphoton Microscopy to Visualize Focused Ultrasound and Microbubble Treatments to Increase Blood-Brain Barrier Permeability

Real-Time Intravital Multiphoton Microscopy to Visualize Focused Ultrasound and Microbubble Treatments to Increase Blood-Brain Barrier Permeability

Published on: February 5, 2022

相关概念视频

Ultrasonography

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...