刺激性肠综合征与非酒精性脂肪肝疾病之间的关联:系统性审查
Jareth Jun Jie Ng1, Wai Mun Loo2, Kewin Tien Ho Siah3,4
1Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
World journal of hepatology
|August 7, 2023
概括
刺激性肠综合征 (IBS) 和非酒精性脂肪肝疾病 (NAFLD) 经常存在联系. 这项审查发现IBS在NAFLD患者中很常见,IBS患者更有可能患NAFLD.
科学领域:
- 胃肠病学 胃肠病学
- 肝病学 肝病学是一种肝病学.
- 代谢疾病 代谢疾病
背景情况:
- 刺激性肠综合征 (IBS) 与肥胖和代谢综合征有关.
- 非酒精性脂肪性肝病 (NAFLD) 和IBS在全球普遍存在.
- 像肠道失调症这样的共享机制可能会连接IBS和NAFLD.
研究的目的:
- 系统地审查IBS和NAFLD之间的联系.
- 遵守系统审查和元分析 (PRISMA) 准则的首选报告项目.
主要方法:
- 搜索了PubMed,EMBASE和Cochrane系统审查数据库.
- 对相关文献进行手动搜索.
主要成果:
- 综述中包括了六项研究.
- 与对照组 (12.5%) 相比,NAFLD患者的IBS发病率较高 (23.2%-29.4%).
- 在IBS患者中,NAFLD患病的可能性是患者的3倍 (65.8%-74.0%).
- 观察到IBS严重程度和NAFLD严重程度之间的相关性.
结论:
- 需要进一步的前性研究来探索IBS-NAFLD关系.
- 调查共享途径可能会导致IBS和NAFLD的新治疗策略.
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