在移植后,肝脏疾病的观点在转变
Iva Kosuta1, Ana Ostojic2, Ana Vujaklija Brajkovic3,4
1Department of Intensive Care Medicine, University Hospital Centre Zagreb, Zagreb 10000, Croatia. ivakosuta@gmail.com.
World journal of hepatology
|August 7, 2023
概括
移植患者的肝脏疾病正在由于新的治疗方法和新出现的COVID-19等病毒而演变. 本综述为有效管理这些肝脏并发症提供了最新的见解.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 肝病学 肝病学是一种肝病学.
- 移植医学 移植医学
背景情况:
- 肝脏疾病是接受移植患者的重要关注点,从轻微的问题到严重的疾病,如肝炎和肝硬化.
- 原因包括病毒感染,药物毒性和代谢障碍,在过去十年中流行率出现了显著的转变.
- 最近在治疗型肝炎,乙型肝炎疫苗接种以及了解药物诱导的肝损伤方面取得的进展,已经改变了这一群体中肝病的局面.
研究的目的:
- 为医疗保健专业人员提供关于最近在接受移植患者肝脏并发症管理方面的进展的全面概述.
- 增强对这种特定患者群体肝病病因和管理策略的理解.
- 支持有关肝脏病移植后肝脏疾病风险和影响的知情决策.
主要方法:
- 本综述综合了当前关于移植患者肝脏疾病的文献和临床指南.
- 它分析了过去十年来肝病病因学的变化.
- 该审查包括新治疗剂和新出现的传染病,如SARS-CoV-2的影响.
主要成果:
- 接受者的肝病病因学发生了显著的变化,受C型肝炎和B型肝炎疫苗接种直接作用抗病毒药物的影响.
- 更好地了解药物诱导的肝毒性和COVID-19大流行所带来的挑战是关键因素.
- 当前的管理策略正在适应这些不断变化的趋势.
结论:
- 医疗保健专业人员需要最新的知识,以有效地管理移植患者的肝脏并发症.
- 有信息的决策需要意识到不断变化的原因和新的治疗选择,以治疗肝脏疾病在这个人群.
- 持续适应病毒感染和与药物相关的毒性对于优化患者的治疗结果至关重要.
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