对患者报告的肥胖结果 (PROS) 问卷的变化敏感性分析:前性队列研究
Pål André Hegland1, Ronette L Kolotkin2,3,4, John Roger Andersen1,4
1Faculty of Health and Social Sciences, Western Norway University of Applied Sciences, Førde, Norway.
Patient related outcome measures
|August 7, 2023
概括
患者报告的肥胖结果 (PROS) 工具有效地测量了减肥手术患者的生活质量变化. 它显示了手术后身体活动,疼痛,睡眠和自尊的显著改善.
科学领域:
- 肥胖研究的研究.
- 腹腔外科手术的结果
- 与健康相关的生活质量 (HRQOL)
背景情况:
- 腹腔外科手术患者往往会减少与健康有关的生活质量.
- 患者报告的肥胖结果 (PROS) 工具是为了评估肥胖的HRQOL而开发的.
- PROS旨在促进在临床咨询期间就患者关注的问题进行对话.
研究的目的:
- 评估患者报告的肥胖结果 (PROS) 工具对变化的敏感性.
- 评估PROS工具在低体重手术后跟踪HRQOL变化的实用性.
- 确定PROS是否可以在患者福祉方面取得有意义的改善.
主要方法:
- 前性研究设计,涉及接受减肥手术的患者.
- 管理PROS和与肥胖有关的问题 (OP) 尺度手术前和手术后3,12和24个月.
- 用于分析PROS和OP得分随时间变化的纵向混合效应模型.
主要成果:
- 在24个月后,在PROS (效果大小-1.34) 和OP (效果大小-1.32) 两种情况下,随着时间的推移观察到显著的变化.
- 大多数患者在手术后24个月报告在所有PROS项目上"不被打扰".
- 身体活动,疼痛,睡眠和自尊心在患者报告的结果中显示出最实质性的改善.
结论:
- 该PROS工具表明敏感性,以改变生命质量后减肥手术.
- PROS是一个简短,易于管理的仪器,适合临床使用.
- 该工具促进了在临床环境中关于肥胖特异性生活质量的对话.
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