对女性生殖器结核病对卵巢储备参数的影响分析
Sharma Richa1, Kanhere Anjali1, Jain Sonal1
1Department of Obstetrics and Gynaecology, Chirayu Medical College and Hospital, Bhopal, Madhya Pradesh, India.
Journal of human reproductive sciences
|August 7, 2023
概括
女性生殖器结核病 (FGTB) 显著降低卵巢储备标记,包括抗穆勒尔激素 (AMH) 和毛囊数 (AFC). 早期诊断和治疗FGTB对于在不育妇女中保持卵巢储备至关重要.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 传染性疾病 传染性疾病
- 妇科 妇科 妇科 妇科
背景情况:
- 女性生殖器结核病 (FGTB) 是导致不孕症的重要原因,在全球影响5%-10%,在印度影响4%-7%.
- 虽然输卵管和子宫内膜损伤是已知的后果,但FGTB对卵巢储备的影响仍然不太了解.
- 卵巢标记物现在有助于评估FGTB患者的卵巢储量.
研究的目的:
- 为了评估不育妇女的卵巢储备,使用抗穆勒尔激素 (AMH) 和毛囊数 (AFC).
- 分析生殖结核病 (GTB) 对这些卵巢储备参数的特定影响.
主要方法:
- 一项在18个月内在第三级不孕症转诊中心进行的前性研究.
- 133名不育妇女接受了宫透视和子宫内膜活检以进行核酸放大测试.
- 测量了AMH和AFC水平,并将FGTB和没有FGTB的女性进行了比较.
主要成果:
- 58名 (43.6%) 妇女 (I组) 诊断出FGTB,75名 (56.3%) 妇女 (II组) 没有FGTB.
- 与II组 (P < 0.001) 相比,I组的AMH (1.88 ng/ml与3.57 ng/ml) 和AFC (9.0与12.50) 的平均值明显较低.
结论:
- 在长期不育和卵巢储备减少的妇女中,应考虑FGTB.
- 及时诊断和治疗GTB可以帮助预防进一步的卵巢储备下降,并改善生育结果.
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