体重调整的腰部指数与血清尿酸之间的关联:一个横截面研究
Huan Li1, Guowei Fang2, Chengcheng Huang2
1First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan 250014, China.
International journal of clinical practice
|August 7, 2023
概括
成年人体重调整的腰指数 (WWI) 与血清尿酸 (SUA) 有正相关,表明中心肥胖和SUA水平之间存在联系. 在一项大型美国研究中,在各种人口群体中观察到这种关联.
科学领域:
- 代谢健康 代谢健康
- 肥胖问题研究研究
- 生物标记分析 生物标记分析
背景情况:
- 血清尿酸 (SUA) 与身体的新陈代谢密切相关.
- 了解SUA升高的预测因素对于代谢健康至关重要.
- 中心的肥胖症在公共卫生方面是一个日益关注的问题.
研究的目的:
- 调查成人体重调整腰部指数 (WWI) 和血清尿酸 (SUA) 之间的关系.
- 评估第一次世界大战作为与SUA相关的代谢障碍的潜在指标.
- 探索 WWI-SUA 关系中的潜在非线性关联和子组差异.
主要方法:
- 利用了2011年至2020年国家健康和营养检查调查 (NHANES) 的6494名符合条件的参与者 (年龄≥20岁) 的数据.
- 采用多变量逻辑回归和子组分析 (年龄,性别,种族) 来检查第一次世界大战和SUA的相关性.
- 应用了合适的光滑曲线,递归算法和两阶段的逐步线性回归来分析非线性关系并确定拐点.
主要成果:
- 在完全调整的模型中,在第一次世界大战和SUA之间发现了显著的正相关性 (β = 5.64).
- 这种积极的关联在按性别,年龄和种族分层的子组分析中仍然存在.
- 在男性和特定的种族/种族群体中观察到非线性关系,包括反转的U形曲线,并确定了拐点.
结论:
- 体重调整的腰部指数 (WWI) 是中心偏重肥胖的一个新型预测指标,独立于整体体重.
- 在第一次世界大战和血清尿酸 (SUA) 之间存在正相关性.
- 第一次世界大战可能成为评估与中心肥胖相关的代谢风险的有价值指数.
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