在输注CD-19定向仿真抗原受体T细胞疗法期间冠状动脉血管:一个病例报告
Jacqueline J Tao1, Natalia Roszkowska2, David T Majure3
1Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, 525 East 68th St, New York, NY 10021, USA.
化学抗原受体T细胞 (CAR-T) 治疗可以导致心血管事件. 一名患者在CAR-T输注期间出现了ST升高心肌梗塞症状,可能是由于冠心血管,突出显示了潜在的心脏毒性.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 心脏病学 心脏病学
背景情况:
- 化学抗原受体T细胞 (CAR-T) 治疗是一种新兴的癌症治疗方法.
- 心血管事件,包括心肌病,心力衰竭,心肌梗塞 (MI) 和心律失常,影响到接受CAR-T治疗的20%的患者.
- 与CAR-T相关的心脏毒性的全谱需要进一步调查.
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