低强度体外冲击波疗法 (LI-ESWT) 在勃起功能障碍患者的有效性
Rayhan Islam1, Khandakar Shafiur Rahaman2,3, Mohammad Delwer Hossain Hawlader4
1School of Health & Life Sciences, North South University, Dhaka, Bangladesh.
Journal of family & reproductive health
|August 7, 2023
概括
低强度体外冲击波疗法 (LI-ESWT) 显示出治疗勃起功能障碍 (ED) 的前景. 这项研究发现,在患有ED的男性接受LI-ESWT治疗后,勃起功能显著改善.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 安德罗学与人类学
- 再生医学是一种再生医学.
背景情况:
- 勃起功能障碍 (ED) 是男性普遍存在的性障碍.
- 目前对ED的治疗选择在有效性和可用性方面有限.
- 需要新的治疗方法来解决ED管理中的未满足需求.
研究的目的:
- 评估低强度体外冲击波疗法 (LI-ESWT) 作为治疗勃起功能障碍的有效性.
- 用国际勃起功能指数 (IIEF-5) 问卷来评估勃起功能的变化.
主要方法:
- 一个预试验性研究设计,只有一个组.
- 参与了31名被诊断患有ED的男性患者.
- 八次LI-ESWT疗程在2-3天的间隔内进行,每次有3000次冲击.
- 在基线和治疗后一个月记录了IIEF-5评分.
主要成果:
- 研究人口的平均年龄为44.6岁,糖尿病 (48.4%) 和高血压 (45.2%) 等并发病的患病率很高.
- 在治疗后,严重ED的患病率从9.7%降至0%,中度ED的患病率从51.6%降至9.7%.
- 观察到IIEF-5得分的统计学上显著改善 (p < 0.001).
结论:
- LI-ESWT在一组ED患者中改善勃起功能方面表现出有效性.
- 这些发现表明LI-ESWT是ED的潜在治疗选择.
- 需要对更大的队列,安慰剂对照和延长后续进行进一步的研究.
相关概念视频
Electroconvulsive Therapy
69
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
69
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
189
Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
189
Male Sexual Response: Erection & Ejaculation
2.8K
Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
2.8K
Disorders of the Male Reproductive System
462
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
462

