代谢综合征和辅助生殖技术
Maryam Kianpour1, Mina Fazlollahi Mohammadi1, Ashraf Kazami1
1Nursing and Midwifery Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Journal of family & reproductive health
|August 7, 2023
概括
代谢综合征对不孕妇女的辅助生殖技术 (ART) 成功率没有影响. 在有代谢综合征和没有代谢综合征的妇女中,怀孕和堕胎率相似,这表明对结果没有重大影响.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 代谢障碍 代谢障碍 代谢障碍
- 不孕症研究 不孕症研究
背景情况:
- 代谢综合征是已知的生殖健康和怀孕结果的危险因素.
- 代谢综合征对辅助生殖技术 (ART) 成功的影响仍未得到充分研究.
研究的目的:
- 研究代谢综合征与不孕妇女的ART成功率之间的关系.
- 确定代谢综合征是否会影响怀孕的成功和早期怀孕的结果.
主要方法:
- 一项前性队列研究,涉及147名在伊朗伊斯法罕接受体外受精/细胞质内精子注射 (IVF/ICSI) 的不育妇女.
- 参与者被分为两组:有代谢综合征 (n=49) 和没有 (n=98).
- 测量了主要的代谢指标 (BMI,腰围/腹围,TG,胆固醇,FBS),并对怀孕结果进行了长达20周的跟踪.
主要成果:
- 在研究参与者中,代谢综合征的患病率为33.4%.
- 在有或没有代谢综合征的妇女之间,在ART成功率,怀孕率 (p=0.907) 或堕胎率 (p=0.896) 中没有发现显著差异.
- 代谢参数根据怀孕或堕胎发生情况没有显著差异.
结论:
- 代谢综合征指标与通过ART实现怀孕的成功率没有显著的关联.
- 该研究发现,在接受ART的具有或没有代谢综合征的女性中,早期怀孕结果 (长达20周) 没有显著差异.
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