与控制性结肠炎营养状况评分和疾病活性相关联
Ziyu Lian1, Jingyi Hu1, Cheng Cheng1
1Department of Gastroenterology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China.
The Journal of international medical research
|August 7, 2023
概括
控制营养状况 (CONUT) 评分可以帮助评估性结肠炎 (UC) 患者的疾病活性. 它反映了炎症反应和营养状况,显示了与关键疾病标志物的相关性.
科学领域:
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
- 炎症性肠病研究研究
背景情况:
- 性结肠炎 (UC) 是一种慢性炎症性肠病.
- 评估UC的疾病活动和营养状况对于管理至关重要.
- 控制营养状况 (CONUT) 评分是评估营养状况的工具.
研究的目的:
- 研究UC患者的CONUT得分和疾病活性之间的关联.
- 为了确定CONUT得分是否可以作为UC疾病活动的生物标志物.
主要方法:
- 对182名UC患者进行了回顾性研究.
- 收集和比较人口,临床和实验室数据.
- 计算CONUT分数并分析与炎症和营养生物标志物的相关性.
主要成果:
- 活跃的UC患者表现出较高的炎症标志物和较低的营养标志物.
- 康得分与营养标记 (血红蛋白,前白蛋白,视网醇结合蛋白) 呈反相关.
- 该CONUT得分与UC疾病活动标志物 (便calprotectin,CRP,ESR,NLR,PLR) 有积极的相关性.
结论:
- CONUT评分可能反映了UC的炎症反应和营养状况.
- CONUT评分显示,它有可能作为评估性结肠炎疾病活性的生物标志物.
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