基于决策树的数据挖掘方法用于评估初级恶性骨瘤的存活率:一项监测,流行病学和最终结果数据库研究研究
Dilek Yapar1,2, Aliekber Yapar3, Mehmet Ali Tokgöz4
1Turkish Ministry of Health, Muratpasa District Health Directorate, Antalya, Turkey.
Journal of orthopaedic surgery (Hong Kong)
|August 7, 2023
概括
这项研究确定了原发性恶性骨瘤 (PMBTs) 的关键预后因素,揭示了阶段,年龄和等级显著影响生存率. 数据挖掘和统计方法证实了这些对患者结果至关重要的因素.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 生物统计学 生物统计学
背景情况:
- 初级恶性骨瘤 (PMBTs) 是一种罕见但具有攻击性的癌症.
- 了解流行病学特征和预后因素对于改善患者的治疗结果至关重要.
研究的目的:
- 对PMBTs进行一项基于人口的大规模研究.
- 通过使用经典的统计和数据挖掘方法来确定流行病学特征和预后因素.
主要方法:
- 使用了国家癌症研究所的SEER数据库 (6234例).
- 采用了卡普兰-梅尔曲线,Log-rank测试和多变量考克斯回归.
- 应用决策树 (DT) 数据挖掘以确认预后因素.
主要成果:
- 对于PMBTs,5年和10年生存率分别为63.6%和55.3%.
- 确定性别,年龄,收入,组织学,部位,等级,阶段,转移和瘤数量作为整体存活 (OS) 的独立风险因素.
- DT分析强调了阶段,年龄和年级作为关键的预后因素,而阶段是最关键的;远期患者的平均存活时间为17个月.
结论:
- 诊断技术为特定患者群体的风险因素提供了有价值的见解,有助于临床决策.
- 建议将DTs与考克斯回归结合用于全面的风险因素分析和生存影响评估.
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