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Updated: Jul 19, 2025

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice
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Published on: June 22, 2016

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双重免疫检查点阻塞诱导了功能障碍的CD8+T细胞和激活的Treg区间的类似变化

Anne M van der Leun1, Joleen J H Traets2, Joris L Vos3

  • 1Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

Cancer discovery
|August 7, 2023
PubMed
概括

新辅助药在头癌中的PD-1/CTLA4阻断改变T细胞的形状. 响应者显示调节性T细胞 (Tregs) 减少和CD8+T细胞改善,而非响应者增加了自然杀手细胞.

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