补充吸血疗法对COVID-19严重和危急患者的有效性:基于证据的分析
Junbing He1, Yao Lin1, Weiming Cai1
1Jieyang Medical Research Center, Jieyang People's Hospital, Jieyang, China.
Shock (Augusta, Ga.)
|August 7, 2023
概括
血液吸收疗法 (HAT) 通过去除细胞因子,显著降低严重的COVID-19患者的死亡率. 然而,在需要体外膜氧化 (ECMO) 支持的患者中没有观察到它的益处.
科学领域:
- 临界护理医学 临界护理医学
- 传染性疾病 传染性疾病
- 生物医学工程 生物医学工程
背景情况:
- 严重的COVID-19可以通过细胞因子风暴引起危及生命的高炎症和组织损伤.
- 身体外血吸疗法 (HAT) 正在探索减轻这些影响,但其有效性仍在争论中.
- 现有研究提出了关于在严重的COVID-19病例中补充HAT的好处的相互矛盾的证据.
结论:
- HAT为严重的COVID-19患者提供临床益处,主要是通过移除细胞因子,从而改善死亡率.
- 在需要ECMO的重症COVID-19患者中,通过HAT进行细胞因子吸附的使用应谨慎处理.
- 进一步的大规模,多中心随机试验是必要的,以验证这些发现,由于现有证据的低质量.
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