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Updated: Jul 19, 2025

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology

Published on: May 2, 2025

雌激素受体和免疫检查点抑制剂:肺癌的新伙伴?

Karmele Valencia^1,2,3,4,5, Luis M Montuenga^1,2,3,5,6, Alfonso Calvo^1,2,3,5,6

¹Program in Solid Tumors, CIMA-University of Navarra, Pamplona, Spain.

Clinical cancer research : an official journal of the American Association for Cancer Research

|August 7, 2023

概括

性别并不决定非小细胞肺癌 (NSCLC) 的免疫治疗反应. 相反,17β-雌激醇/ERα/PDL1信号循环是关键,为NSCLC治疗提供了新的治疗途径.

科学领域:

在瘤学瘤学.
免疫学免疫学免疫学
内分泌学在内分泌学.

背景情况:

关于非小细胞肺癌 (NSCLC) 免疫治疗反应的性别差异的先前研究得出了不确定的结果.
对于个性化医学来说,研究在NSCLC治疗疗效背后的生物机制至关重要.

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Patient-Derived Tumor Explants As a "Live" Preclinical Platform for Predicting Drug Resistance in Patients

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