在骑自行车运动期间,热量对一氧化碳 (DLCO) 的肺扩散能力的影响
Mirelle I Schoeberlein1, Catherine E Frisiras1, Kirsten E Coffman2
1Department of Exercise Science, University of Puget Sound, Tacoma, WA, USA.
European journal of applied physiology
|August 7, 2023
概括
运动期间的热暴露意外增加了肺部对一氧化碳 (DLCO) 的扩散能力. 这表明,在炎热的运动中,肺部血流和气体交换的增强.
科学领域:
- 运动生理学 运动生理学
- 环境生理学环境生理学
- 肺部医学 肺部医学
背景情况:
- 运动期间暴露于热量会改变生理反应.
- 肺血流调节对于体力活动期间的气体交换至关重要.
- 一氧化碳的肺扩散能力 (DLCO) 是肺血流和气体交换效率的间接指标.
研究的目的:
- 量化热暴露和增加运动强度对肺血流的综合影响.
- 为了研究在热中和热条件下炼期间DLCO的变化.
- 为了测试假设,增加皮肤热血流量会减少肺血流和DLCO.
主要方法:
- 9名健康受试者 (4F/5M) 在休息状态下进行了自行车运动,20%和40%的最大工作负载 (Wmax).
- 测量是在热中性 (22.2°C) 和热 (39.4°C) 条件下进行的.
- 测量的关键参数包括DLCO,每分钟通风 (VE),氧气消耗,心率 (HR) 和核心/皮肤温度.
主要成果:
- DLCO显示了运动强度和热量之间的显著相互作用,在热量中40%的Wmax时更高 (P=0.003).
- 在热和热中性条件之间,每分钟的通风和氧气消耗没有差异.
- 心率在炎热时显著上升 (P<0.001),核心和皮肤温度与温度和强度有显著的相互作用.
结论:
- 与假设相反,DLCO在高温运动期间增加.
- 这表明气体交换的肺表面面积更大,可能是由于肺毛细血管招募或膨胀的增加.
- 这些发现增强了对热量对DLCO评估的肺血流的影响的理解.
更多相关视频
相关概念视频
Assessment of Diffusion and Perfusion
1.0K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
1.0K
Oxygen Transport in the Blood
2.8K
Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...
2.8K
External and Internal Respiration
4.1K
External respiration occurs in the lungs, and it is the first step in the journey of oxygen inside the body. When we inhale, oxygen enters our lungs and diffuses across the thin alveolar membrane. The alveoli are tiny, air-filled sacs that provide a vast surface area for gas exchange. Oxygen in the alveoli has a higher partial pressure (105 mmHg) than in the adjacent pulmonary capillaries (40 mmHg), establishing a pressure gradient. As a result, oxygen molecules move from the alveoli into the...
4.1K
Gas Exchange and Transport
70.3K
Gas exchange, the intake of molecular oxygen (O2) from the environment and the outflow of carbon dioxide (CO2) into the environment, is necessary for cellular function. Gas exchange during respiration occurs largely via the movement of gas molecules along pressure gradients. Gas travels from areas of higher partial pressure to areas of lower partial pressure. In mammals, gas exchange occurs in the alveoli of the lungs, which are adjacent to capillaries and share a membrane with them.
70.3K
Factors Affecting Pulmonary Ventilation
1.4K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.4K
Carbon Dioxide Transport in the Blood
2.1K
Carbon dioxide (CO2) transport in the blood is critical to human physiology. On average, our body cells produce around 200 mL of CO2 per minute, precisely the quantity expelled by the lungs. This process involves the transportation of CO2 from the tissue cells to the lungs in three primary forms.
Forms of CO2 Transport
1. Dissolved in plasma: A small percentage (7-10%) of CO2 is transported and dissolved directly in the plasma.
2. Carbaminohemoglobin: Just over 20% of CO2 is chemically bound to...
Forms of CO2 Transport
1. Dissolved in plasma: A small percentage (7-10%) of CO2 is transported and dissolved directly in the plasma.
2. Carbaminohemoglobin: Just over 20% of CO2 is chemically bound to...
2.1K


