肺动脉弹性降低的预测值在急性肺栓塞中用于右心室功能障碍
Fei Yang1, Rong Chen2, Zhixiang Yang2
1Department of Medical Imaging, the First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, 075000, China.
Journal of thrombosis and thrombolysis
|August 7, 2023
概括
通过CTPA测量的大动脉张力 (AD) 可以帮助评估急性肺栓塞 (APE) 患者的右心室功能障碍 (RVD). 这种成像技术有助于及时诊断和治疗,改善患者的治疗结果.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 肺部医学 肺部医学
背景情况:
- 计算机断层扫描肺血管学 (CTPA) 用于急性肺栓塞 (APE) 的风险分层,使用诸如右心室/左心室 (RV/LV) 比率之类的指数.
- 肺动脉弹性 (PAE) 已被描述,但其与右心室功能障碍 (RVD) 的关联仍然未被探索.
研究的目的:
- 为了调查PAE,特别是通过CTPA测量的大动脉张张 (AD),是否与APE患者的RVD有关.
主要方法:
- 对APE患者进行了回顾性心电图带入的CTPA.
- 根据心声学,患者被分为RVD和非RVD组.
- PAE参数 (AD,大动脉顺应,大动脉硬) 和右心功能指数进行了比较和相关联.
- 使用接收器操作特征 (ROC) 曲线来评估RVD预测准确性.
主要成果:
- 与非RVD组相比,在RVD组观察到减少的AD (P <0.05).
- 几种右心功能指数,包括RV/LV直径和体积比,在RVD组显著更高.
- 在预测RVD时,AD与指示RVD的参数有显著的负相关性,ROC分析给出了AD在0.748的曲线下的面积.
结论:
- 来自CTPA的大动脉张张 (AD) 是评估APE患者RVD的潜在成像生物标志物.
- 这一发现可以帮助及时诊断和管理APE,从而有可能改善患者的预后.
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