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Updated: Jul 19, 2025

Reconstitution of Actin-Based Motility with Commercially Available Proteins
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过渡状态的Arp2/3复合体激活由Actin-Bound Dimeric核化促进因子激活

Trevor van Eeuwen1, Malgorzata Boczkowska2, Grzegorz Rebowski2

  • 1Biochemistry and Molecular Biophysics Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.

Proceedings of the National Academy of Sciences of the United States of America
|August 7, 2023
PubMed
概括

对于细胞运动至关重要的Arp2/3复合体,通过辅因子过渡到活性状态. 这项研究揭示了其中间结构,澄清了这些辅助因子如何协调分支性动因子网络的激活.

关键词:
Arp2/3 复合体是一个复合体.这就是Actin Actin.激活机制的激活机制低温电磁波冷却器 (Cryo-EM) 是一个非常好的方法.

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