记录了青素过敏对抗生素选择在儿科急诊室的访问
Eileen J Carter1, Katherine Zavez2, Steven C Rogers3
1From the University of Connecticut School of Nursing, Storrs, CT.
Pediatric emergency care
|August 7, 2023
概括
在儿童中报告的青素过敏显著增加了广谱抗生素的使用. 在儿科急诊室重新标记这些常见的,往往不准确的过敏症是抗生素管理的关键目标.
科学领域:
- 儿科急救医学 儿科急救医学
- 传染性疾病 传染性疾病
- 临床药理学 临床药理学
背景情况:
- 青素和阿莫西西林是常见的儿科细菌感染的第一线治疗方法.
- 报告的青素过敏在儿童中很常见,但往往不准确.
- 这项研究调查了报告的青素过敏对儿科急诊室抗生素选择的影响.
研究的目的:
- 为了评估报告的青素过敏如何影响儿童急诊室 (ED) 访问的广泛抗生素使用.
- 评估报道的青素过敏对急性中耳炎 (AOM) 和A型 estreptococcus (GAS) 喉炎的抗生素选择的影响.
主要方法:
- 2014年至2016年的儿科病人的回顾性队列研究,在一个大型儿科ED.
- 分析电子医疗记录以识别报告有青素过敏的患者.
- 使用概括估计方程和后勤回归模型来分析抗生素选择和治疗概率.
主要成果:
- 在12,987名儿科患者中,6.2%的儿童有记录的青素过敏.
- 报告的青素过敏与接受广谱抗生素的几率增加了13.55倍.
- 记录有青素过敏的儿童接受AOM和GAS的替代治疗的概率为0.97.
结论:
- 报告的青素过敏显著推动了儿童ED中使用宽谱抗生素.
- 重新标记青素过敏,特别是急性呼吸道感染,是潜在的抗生素管理干预措施.
- 针对青素过敏的"脱标"可以改善儿科护理中的抗生素处方实践.
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