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Updated: Jul 19, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
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一种LC-ESI-MS/MS方法用于在低体积血和脑脊液中测定丹塞:方法开发,验证和临床应用

Anna Siemiątkowska1, Karen Frey2, Katharine N Gurba2

  • 1Department of Pharmaceutics and Center of Excellence for Pharmaceutical Translational Research and Education, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA; Department of Physical Pharmacy and Pharmacokinetics, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznań, Poland.

Journal of pharmaceutical and biomedical analysis
|August 7, 2023
PubMed
概括

这项研究开发了一种敏感的LC-MS/MS方法,用于测量人类血和脑脊液 (CSF) 中的丹塞. 这种方法对于理解ondansetron至关重要.

关键词:
它是5-HT3受体对手.测试验证的验证方法空白矩阵是一个空白矩阵.转载-转载-转载-转载方法的比较方法的比较.这是一种P-glycoprotein蛋白.

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