达帕格利弗洛辛可以防止与氧化通路相关的多克索鲁比辛诱导的毒性-A转化研究

Wei-Ting Chang1, Chia-Chun Wu2, I-Chuang Liao3

  • 1School of Medicine and Doctoral Program of Clinical and Experimental Medicine, College of Medicine and Center of Excellence for Metabolic Associated Fatty Liver Disease, National Sun Yat-sen University, Kaohsiung, Taiwan; Division of Cardiology, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan; Department of Biotechnology, Southern Taiwan University of Science and Technology, Tainan, Taiwan.

PubMed
概括

达帕格利弗洛辛 (DAPA) 可能会防止多克索鲁比辛 (Dox) 诱导的损伤. 这项研究发现DAPA降低了Dox治疗的老鼠和细胞的功能,改善了功能,这表明DAPA可以预防Dox毒性.

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