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Updated: Jul 19, 2025

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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Published on: July 28, 2017

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天然的深溶性溶剂保护RNA免受热引起的降解

Roberto Mattioli1, Anna Maggiore2, Daniel Di Risola1

  • 1Department of Biochemical Sciences, Sapienza University of Rome, 00185, Rome, Italy.

Archives of biochemistry and biophysics
|August 7, 2023
PubMed
概括

天然深层阳性溶剂 (NaDES) 可以稳定易降解的RNA分子,特别是在高温下. 这种方法提高了RNA的稳定性,用于mRNA疫苗和基因治疗中的应用.

关键词:
在 DES DES 中,您可以使用纳德斯 (NaDES) 的时间热降解RNA的热降解

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