动脉复血管化的认知影响在八十岁的八十岁人群中
Bahaa Succar1, Ying-Hui Chou2, Chiu-Hsieh Hsu3
1Department of Surgery, Division of Vascular Surgery, The University of Arizona, Tucson, AZ.
Surgery
|August 7, 2023
概括
动脉干预有益于年轻患者,但在八十岁以上 (≥80岁) 的患者中没有表现出认知改善. 这一老年人群需要进一步的研究,以了解在 carotid revascularization 后的认知变化.
科学领域:
- 神经学 神经学
- 血管外科 血管外科
- 老年病的医生 老年病的医生
背景情况:
- 认知障碍是脑血管疾病的主要后果之一.
- 动脉干预对于严重的动脉动脉样硬化有前途.
- 经过动脉再血管化的八十岁人的神经认知结果仍然不清楚.
研究的目的:
- 为了评估经干预后的认知变化,80岁及以上的患者接受了动脉干预.
- 为了比较八十岁和非八十岁患者之间的认知结果.
主要方法:
- 对170名接受动脉手术的患者进行前性研究.
- 在手术前和1,6,12个月后进行神经认知测试 (口语记忆,执行功能,语言).
- 八十岁 (≥80岁) 和非八十岁 (<80岁) 之间的认知分数的比较.
主要成果:
- 八代人 (n=23) 在干预后12个月内没有表现出语言记忆,执行功能或语言的显著认知改善.
- 年轻患者 (n=147) 在干预后表现出显著的认知改善.
- 八十多岁的群体占研究样本的13%.
结论:
- 动脉干预可以增强患有动脉封闭性动脉样硬化症的年轻患者的认知功能.
- 在八十多岁的患者中,在 carotid 干预后没有观察到认知益处.
- 进一步的研究是必要的,以了解八十岁的认知变化后revascularization.
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