心脏MRI上的T2*图显示了偶尔发生的肝脏和心脏铁过载
Jan M Brendel1, Alina Kratzenstein1, Josephine Berger1
1Department of Radiology, Diagnostic and Interventional Radiology, University of Tübingen, 72076 Germany.
Diagnostic and interventional imaging
|August 7, 2023
概括
心脏磁共振 (CMR) T2*映射偶尔检测到3.9%的肝脏铁过载和1.1%的心脏铁过载患者. 这种成像技术可能有助于管理意外铁积累的患者.
科学领域:
- 心血管成像 - 心血管成像
- 放射学 放射学是一门学科.
- 医学诊断 医学诊断 医学诊断
背景情况:
- 铁的过载会导致严重的器官损伤.
- 早期检测铁积累对于有效的患者管理至关重要.
- 心脏磁共振 (CMR) T2*映射是一种评估组织铁度的非侵入性技术.
研究的目的:
- 评估CMR T2*映射在识别意外肝脏和心脏铁过载时的诊断性能.
- 为了确定在患者队列中通过CMR T2*映射检测到的偶然铁过载的患病率.
- 通过读者间协议分析评估T2*测量的可靠性.
主要方法:
- 一项前性研究包括614名患者,他们接受了常规的1.5TCMR,并对心脏和肝脏进行T2*映射.
- 铁过载被分为轻度,中度或严重,基于T2*值 (ms).
- 对T2*测量的读者间一致性使用类内相关系数 (ICC) 进行评估.
主要成果:
- 在3.9%的患者中发现了偶然的肝脏铁过载 (轻度:3.6%,中度:0.3%).
- 在1.1%的患者中检测到偶然的心脏铁过载 (轻度:0.8%,中度:0.2%,严重:0.2%).
- 对心脏 (ICC:0.90) 和肝脏 (ICC:0.91) T2*测量均观察到优异的读者间一致性.
结论:
- 标准CMR T2*映射有效地检测意外的心脏和肝脏铁过载.
- 这些发现表明,T2*成像应该考虑将其纳入全面的CMR协议.
- 通过CMR T2*映射检测到的偶然的铁过载可能需要进一步的患者管理和监测.
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