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在美国人口中对类脏细胞癌的人口结构模式和临床病理学分析

Asad Ullah¹, Abdul Qahar Khan Yasinzai², Om V Sakhalkar³

¹Department of Pathology, Texas Tech University Health Sciences Center, Lubbock, TX.

Clinical genitourinary cancer

|August 7, 2023

概括

类细胞癌 (RCC) 主要影响老年白人男性. 晚年,远期和大型瘤与预后不佳有关,而手术改善了生存结果.

科学领域:

在瘤学瘤学.
尿道瘤学尿道瘤学
癌症流行病学癌症流行病学

背景情况:

类细胞癌 (RCC) 是一种罕见的癌变体,其特征是存在类成分.
了解影响肉 Sarcomatoid RCC 预后的临床,人口和病理因素对于患者管理至关重要.

研究的目的:

总结了sarcomatoid RCC患者的临床,人口和病理因素.
为了确定影响类RCC预后和存活率的人口差异.
分析一大群类RCC患者的治疗结果和生存率.

主要方法:

使用了监测,流行病学和最终结果 (SEER) 数据库.
汇编了2000年至2018年期间被诊断患有类RCC的2695名患者的数据.
进行多变量分析以确定死亡率的独立风险因素.

主要成果:

类RCC主要诊断在白人男性 (82.6%白人,68.2%男性) 中,平均年龄为62.8岁.
在诊断时,显著比例的瘤是大 (>10厘米,36.4%) 和远程 (55.8%) 的.
整体5年生存率为18.1%,但在接受手术的患者中改善到27.1%. 独立的死亡风险因素包括年龄> 60,远程阶段和瘤大小> 10厘米.

结论:

类RCC最常影响70多岁的白人男性.
增加的年龄,遥远的阶段和更大的瘤大小 (>10厘米) 与不良的预后有关.
手术干预,特别是在局部疾病中,以及多模式治疗与改善的生存结果相关.

关键词:

转移转移转移转移多模式疗法多模式疗法多变量是多变量的.塞尔 (Seer) 是一个明星.生存结果的结果.

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