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Updated: Jul 19, 2025

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
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Published on: October 23, 2018

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需要TET2来抑制通过尿素循环的mTORC1信号传递,具有治疗潜力

Jing He1, Mingen Lin1, Xinchao Zhang1

  • 1MOE Key Laboratory of Metabolism and Molecular Medicine, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China.

Cell discovery
|August 7, 2023
PubMed
概括

通过抑制mTORC1信号传递,TET2 (十-十一转位2) 抑制细胞生长. 瘤中的TET2缺乏增加了对mTORC1抑制剂的敏感性,这表明了潜在的治疗策略.

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