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基于严重程度的癌症相关疲劳的流行:系统性审查和元分析
Ye-Eun Kang1, Ji-Hae Yoon1, Na-Hyun Park1
1Research Center for CFS/ME, Daejeon Oriental Hospital of Daejeon University, Daejeon, Republic of Korea.
Scientific reports
|August 7, 2023
概括
与癌症相关的疲劳 (CRF) 影响了许多患者,整体疲劳患病率为43.0%. 严重的疲劳因癌症类型,治疗和患者的性别而异,这突显出需要量身定制的护理.
科学领域:
- 在瘤学瘤学.
- 临床研究 临床研究
- 公共卫生 公共卫生
背景情况:
- 与癌症相关的疲劳 (CRF) 显著影响治疗坚持和患者的结果,包括生存率.
- 了解CRF的患病率和严重程度对于有效的患者管理至关重要.
研究的目的:
- 进行综合性,比较性评估,以癌症相关疲劳的严重程度为基础的流行.
- 分析CRF患病率和严重程度如何根据瘤类型,治疗阶段,治疗,性别和评估方法而有所不同.
主要方法:
- 对从PubMed和Cochrane图书馆提取到2021年12月的数据进行了元分析.
- 包括57项与34,310名参与者的研究,分析了癌症患者疲劳的患病率和严重程度.
- 亚组分析检查了根据癌症起源,治疗阶段,治疗类型,性别和评估视角的变化.
主要成果:
- 整体疲劳患病率为43.0%;包括轻度病例,CRF患病率达到70.7%.
- 严重疲劳的患病率因癌症类型 (例如,脑瘤39.7%与妇科瘤3.9%) 和治疗阶段而异.
- 化疗显示严重的CRF患病率 (33.1%) 比手术 (22.0%) 或放射治疗 (24.2%) 高.
- 自我报告的严重CRF (23.6%) 是医生评估的20倍 (1.6%). 女性患者的严重CRF患病率比男性高1.4倍.
结论:
- 癌症特异性因素,治疗方式,患者的性别和评估方法影响了CRF的患病率和严重程度.
- 结果为医疗保健提供者提供了定量参考,以便在CRF管理方面做出明智的,针对患者的决定.
- 这项研究强调了以患者为中心的方法在解决与癌症相关的疲劳方面的重要性.
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