机械通风期间30% vs. 60%启发氧气分数对术后脱氧的作用:一项随机对照试验
Zhaoshun Jiang1,2, Songbin Liu1,2, Lan Wang1
1Department of Anesthesiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
BMC anesthesiology
|August 7, 2023
概括
在机械通风过程中将吸入氧分数 (FiO2) 降低到30%,与60%的FiO2相比,没有降低术后吞吐量. 这项研究发现,这两种氧气度之间的肺脱氧量没有显著差异.
科学领域:
- 麻醉学 麻醉学
- 关键护理医学 关键护理医学
- 肺部医学 肺部医学
背景情况:
- 手术后的脱氧症是机械通风后的一个常见并发症.
- 最佳的灵感氧气分数 (FiO2) 减轻脱氧症仍在争论中.
- 这项研究研究了低 (30%) 与中度 (60%) FiO2对术后肺部变化的影响.
研究的目的:
- 为了比较30%的FiO2和60%的FiO2对手术后骨质疏散体积的影响.
- 评价二次结果,包括通风量和显著的 atelectasis 的发生率.
主要方法:
- 一项随机对照试验,涉及120名接受机械呼吸的患者.
- 患者被分配接受30%或60%的FiO.
- 术后的骨质疏散体积用胸部CT测量,测量是在输出管后30分钟内进行的.
主要成果:
- 113名患者完成了试验 (55名在30%的FiO2组中,58名在60%的FiO2组中).
- 在30%和60%的FiO2组之间没有观察到 postoperative atelectasis体积百分比的显著差异.
- 二级结局,包括通风量和临床显著的脱酶发生率,也没有显著差异.
结论:
- 在机械通风过程中使用30%的FiO2并不能减少术后的骨质疏通体积,相比之下,60%的FiO2.
- 选择30%或60%的FiO2并没有影响肺气化或显著的脱酶的发生率.
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