相关实验视频
Updated: Jul 19, 2025

11:18
Direct Drug Delivery to Kidney via the Renal Artery
Published on: April 17, 2021
7.4K
关于高血压药物输送系统的最新见解:从银行到市场
Gaurav Sharma1, Abhishek Sharma1
1University Institute of Pharma Sciences (UIPS), Chandigarh University, Gharuan, Punjab-140413, India.
Current hypertension reviews
|August 8, 2023
概括
高血压影响全球超过10亿人,是中风和心力衰竭的主要危险因素. 本综述探讨了用于管理高血压的先进治疗方法,包括纳米技术和人工智能.
科学领域:
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
- 医疗技术 医疗技术 医学技术
背景情况:
- 高血压是全球主要的健康问题,增加了心血管疾病,功能衰竭和脑疾病的风险.
- 传统的抗高血压药物有其局限性和副作用.
- 印度在高血压诊断率方面面临重大挑战.
研究的目的:
- 审查印度高血压的流行病学.
- 讨论高血压的病理生理学和当前/新型治疗策略.
- 探索纳米技术,智能设备和人工智能在高血压管理中的作用.
主要方法:
- 关于印度高血压的流行病学数据的文献综述.
- 对传统和新型抗高血压药物类别的分析.
- 基于纳米技术的药物输送系统对高血压的检查.
- 对人工智能和用于高血压治疗的智能设备等新兴技术的审查.
主要成果:
- 高血压是一个关键的全球健康问题,诊断率差异显著.
- 像ACE2和APA抑制剂这样的新方法,以及纳米技术,显示出希望.
- 智能设备和人工智能为个性化和改进的高血压管理提供了潜力.
结论:
- 先进的治疗策略,包括纳米技术和人工智能,对于有效的高血压管理至关重要.
- 解决全球高血压负担需要探索创新的治疗方式.
- 未来的高血压治疗可能会整合智能设备和人工智能,以改善患者的治疗结果.
相关概念视频
Drug Delivery: Miscellaneous Routes
381
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
381
Drug Delivery: Overview
322
The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
322
Drug Delivery: Enteral Route
505
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
505
Antihypertensive Drugs: Direct Renin Inhibitors
682
The renin-angiotensin-aldosterone system (RAAS) is an intricate physiological pathway involving numerous enzymes and hormones, including renin, angiotensin-converting enzyme (ACE), angiotensin I and II, and aldosterone. Imbalances within this system increase the production of angiotensin II and aldosterone. Increased angiotensin II levels promote vasoconstriction and blood pressure elevation. Concurrently, higher aldosterone levels stimulate sodium and water reabsorption in the kidneys,...
682
Hypertension IV: Drug Therapy and Lifestyle Modifications
14
Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
14
Antihypertensive Drugs: Vasodilators
566
Vasodilators, primarily affecting the smooth muscles within arterial and venous walls, are commonly used for hypertension treatment. Medications such as minoxidil and hydralazine primarily target arteries and arterioles, while sodium nitroprusside acts on arterioles and venules. Minoxidil, functioning as a prodrug, is metabolized by hepatic sulfotransferase into its active form, minoxidil sulfate, after oral administration. This metabolite binds to the sulfonylurea receptor (SUR) component of...
566

