弱种子库影响选择性扫描的签名和可检测性
Kevin Korfmann1, Diala Abu Awad1,2, Aurélien Tellier1
1Department of Life Science Systems, School of Life Sciences, Technical University of Munich, München, Germany.
Journal of evolutionary biology
|August 8, 2023
概括
种子储存,一种投注对冲策略,改变了基因漂移和选择特征. 我们的模拟表明,它延长了固定时间,但缩小了扫地足迹,有助于在休眠物种中的进化推断.
科学领域:
- 进化生物学是进化的生物学.
- 人口遗传学 人口遗传学
- 基因组学就是基因组学.
背景情况:
- 种子银行是一种投注对冲策略,影响人口重叠和遗传漂移.
- 目前用于检测选择性扫描的方法通常会因为方法的复杂性而忽略种子储存.
- 种子休眠可以改变祖先重组图 (ARG),影响基因组选择的签名.
研究的目的:
- 研究种子储存如何影响有益等位基因的动态和基因组足迹.
- 确定种子储存是否影响选择和核酸多样性模式的有效性.
- 开发一个模拟工具来分析种子库中的物种选择.
主要方法:
- 开发了第一个基于树序的模拟程序,其中包含一个弱种子库.
- 在具有休眠状态的有限群体中模拟了有益等位基因动态.
- 分析了固定概率,固定时间和核酸多样性模式.
主要成果:
- 种子储存不会影响有利的等位基因固定的概率.
- 种子储存增加了固定时间,但与预期相比缩短了它们,而不考虑亲生繁殖的有效种群规模.
- 由于种子储存增加了有效重组率,导致更长时间检测到的更窄的扫描足迹.
结论:
- 种子储存显著影响了基因组足迹的选择,使扫描看起来更窄,更长的可检测.
- 开发的模拟工具可以预测选择足迹,并有助于推断种子储存生物体的进化历史.
- 了解种子储存对于准确检测不同种类中的正选择至关重要.
相关概念视频
Frequency-dependent Selection
22.1K
When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
22.1K
Types of Selection
40.6K
Natural selection influences the frequencies of particular alleles and phenotypes within populations in several different ways. Primarily, natural selection can be directional, stabilizing, or disruptive. Directional selection favors one extreme trait and shifts the population towards that phenotype while selecting against individuals displaying alternate traits. Stabilizing selection favors an intermediate trait with a narrow range of variation. Deviation from the optimal phenotype towards an...
40.6K
Genetic Drift
39.9K
Natural selection—probably the most well-known evolutionary mechanism—increases the prevalence of traits that enhance survival and reproduction. However, evolution does not merely propagate favorable traits, nor does it always benefit populations.
39.9K
Mutation, Gene Flow, and Genetic Drift
58.5K
In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
58.5K
Conservation of Small Populations
13.2K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
13.2K
What is Natural Selection?
115.6K
Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.
115.6K


