处方分析强调抗生素对下呼吸道感染的药物坚持
Sanatkumar Bharamu Nyamagoud1, A H M Viswanatha Swamy2, Anchu S P3
1Department of Pharmacy Practice, KLE College of Pharmacy Hubballi, a constituent unit of KLE Academy of Higher Education and Research, Belagavi, Karnataka . dr.sanathnyamagoud@gmail.com.
这项研究研究了针对下呼吸道感染 (LRTI) 的抗生素处方,发现了合理的处方数量,但强调了减少多药的必要性,以改善患者的坚持.
科学领域:
- 药理学 药理学是指药理学的学科.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 抗生素耐药性是一个主要的公共卫生问题.
- 不合理的抗生素使用有助于耐药性和治疗失败.
- 了解处方模式对于优化LRTI管理至关重要.
研究的目的:
- 在一般人群中分析下呼吸道感染 (LRTI) 的抗生素处方模式.
- 为了评估患者对处方抗生素治疗的坚持.
- 确定在抗生素处方实践中需要改进的领域.
主要方法:
- 从2021年11月到2022年4月进行了前性观察研究.
- 收集了有关患者人口统计,诊断,处方抗生素和住院时间的数据.
- 使用MMAS-4尺度评估了药物坚持.
主要成果:
- 总共有200名患者被纳入,其中53%是男性,47%是女性.
- 塞夫特里亚克松是最常被处方的抗生素,其次是阿齐思罗米和皮佩拉西林/塔扎巴克坦.
- 支气管肺炎 (41%) 和慢性阻塞性肺部疾病 (AECOPD) 的急性恶化 (28%) 是最常见的诊断. 药物坚持度很高 (58%),但在11%的患者中观察到不良坚持.
- 虽然每位患者处方的抗生素数量被认为是合理的,但多药制是普遍存在的.
结论:
- 在这个人群中,对LRTIs的抗生素处方通常是合理的,但需要解决多药性.
- 减少抗生素的频率可以提高患者的服药性,并可能改善治疗结果.
- 需要进一步的战略来打击不合理的抗生素使用和促进坚持.
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