第一个三个月的综合测试结果与甲状腺刺激激素水平之间的相关性以及对怀孕结果的影响
Ezgi Ozsoz Kolsuz1, Dilek Uysal2, Aysegul Gulbahar2
1Department of Obstetrics and Gynecology, Kutahya University of Health Sciences, Evliya Celebi Training and Research Hospital, Kutahya, Turkey.
Iranian journal of public health
|August 8, 2023
概括
甲状腺刺激激素 (TSH) 和第一季度联合查测试可以预测怀孕结果. 自由β-人类胆性淋巴激素 (β-hCG) 和TSH水平可能分别表明新生儿出生体重和分娩时间.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 第一个三个月的联合查测试和甲状腺刺激激素 (TSH) 对于评估怀孕结果至关重要.
- 执业者需要明确影响早期怀孕的独立预后因素.
- 对健康的孕妇来说,评估TSH和综合查测试水平之间的相关性至关重要.
研究的目的:
- 评估TSH水平与第一季度综合查试验结果之间的相关性.
- 检查TSH和联合查测试对健康妇女怀孕结果的影响.
- 为了确定怀孕结果的独立预后因素.
主要方法:
- 研究了一组349名健康的孕妇,他们的TSH值在第一季度正常.
- 参与者根据TSH水平 (切断值2.5uIU/ml) 和妊娠周进行了分组分析.
- 他们比较了出生体重,怀孕周,TSH值和综合测试参数 (包括自由β-人类胆性淋巴激素[β-hCG]).
主要成果:
- 结合测试参数和TSH水平之间没有发现显著的关系,当TSH值被分组时.
- 在怀孕11周后观察到自由β-hCG和TSH之间的负相关性 (P=0.040,r=-0.189).
- 自由β-hCG与新生儿出生体重负相关 (P=0.032,r=-0.199),而TSH与分娩时间负相关 (P=0.011,r=-0.235).
结论:
- 自由β-hCG和TSH水平可以潜在地指导新生儿分别出生体重和分娩时间的预测.
- 血清TSH水平升高可能需要将联合测试推迟到怀孕12-13周,以减少错误阳性.
- 这些发现提供了关于利用早期怀孕标志物的见解,以改善结果预测.
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