专和功能化专纳米颗粒:生产策略,表征和目标指示

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Abhishek Srivastava¹, Anjali Prajapati²

¹Department of Chemistry, GLA University, Chaumuhan, Mathura, Uttar Pradesh281406, India.

Asian biomedicine : research, reviews and news

|August 8, 2023

概括

专纳米颗粒提供了一个生物相容的平台,用于药物输送,因为它们的表面积很大,并且能够准特定的位置. 本综述探讨了它们的生产,药物加载和释放模式,以增强治疗应用.

科学领域:

生物材料科学生物材料科学
纳米技术纳米技术
药物输送系统药物输送系统

背景情况:

专的固有特性使其适合创建纳米尺寸的药物输送载体.
专纳米粒子提供增强的表面积,生物相容性和延长的半衰期.
专可以与配体结合,用于向药物输送.

研究的目的:

审查专和结合专纳米颗粒的生产策略.
讨论针对特定器官和癌细胞的向策略.
为了解药物加载,释放模式和细胞毒性提供见解.

主要方法:

关于蛋白纳米粒子制剂的现有文献的综述.
对有针对性的交付的结合技术的分析.
药物加载和释放机制的评估.
对各种药物载的专胺纳米颗粒的细胞毒性数据的评估.

主要成果:

专纳米粒子是具有可调节性质的有效药物输送载体.
结合增强了针对特定细胞和器官的向效率.
药物加载和释放动力学受到纳米粒子配方的影响.
细胞毒性概况因纳入药物和纳米颗粒设计而异.

结论:

专纳米颗粒代表了针对药物输送的有希望的平台.
进一步研究生产,准和药物负载优化是有必要的.
基于白蛋白的纳米载体显示出改善癌症治疗和器官特异性治疗的潜力.

关键词:

专辑蛋白 (albumin) 是一种药物输送系统是药物输送系统.毒品的解放毒品的解放纳米颗粒是一种纳米粒子.这些都是新生儿瘤.

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