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Updated: Jul 19, 2025

Chromatin Isolation by RNA Purification ChIRP
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染色体读取器ORCA/LRWD1在将原始识别复合体定位为染色体的双重作用

Sumon Sahu1, Babatunde E Ekundayo1, Ashish Kumar1

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.

The EMBO journal
|August 8, 2023
PubMed
概括

原始识别复合体 (ORC) 相关的蛋白质ORCA将ORC招募到异染色质中,用于DNA复制. 在ORCA中,核细胞与特定的基因素标记结合在一起,从而促进复制的启动.

关键词:
染色是一种染色素.启动DNA复制的开始在MCM2-7的加载过程中.原产地许可证的授权.复杂的原产地认可复合体

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