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Updated: Jul 19, 2025

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

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恢复神经元化物挤出可以逆转与阿尔茨海默病突变相关的认知衰退

Iason Keramidis1,2, Brendan B McAllister3, Julien Bourbonnais1

  • 1CERVO Brain Research Centre, Quebec Mental Health Institute, Québec, QC G1E 1T2, Canada.

Brain : a journal of neurology
|August 8, 2023
PubMed
概括

早期的阿尔茨海默氏症涉及KCC2载体的损失,这对大脑抑制至关重要. 在小鼠模型中恢复KCC2功能逆转了认知衰退和社会功能障碍.

关键词:
应用 NL-G-F/NL-G-F 在线5xFADAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5xFAD 5XFAD 5XFAD 5XFAD 5XFAD 5XFAD 5XFAD 5XFAD 5XFAD 5XFAD 5XFAD 5XFD阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.在KCC2中,KCC2是KCC2.化物常态稳定 化物常态稳定抑制抑制抑制的抑制作用

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