在特殊人群中治疗酒精使用障碍的药物治疗
Aniket Malhotra1, Karen Drexler1, Michael Hsu1
1Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia, USA.
The American journal on addictions
|August 8, 2023
概括
有效的酒精使用障碍 (AUD) 治疗方法存在,但在特殊人群中使用不足. 考虑到独特需求的定制方法对于改善不同群体AUD治疗结果至关重要.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 酒精使用障碍 (AUD) 是一个重大的公共卫生挑战.
- 对AUD的有效治疗方法未得到充分利用,特别是在特殊人群中.
- 本综述侧重于针对不同患者群体的基于证据的AUD治疗指南.
研究的目的:
- 综合当前的证据和指导方针来治疗特殊人群中的AUD.
- 突出在不同的人口和临床群体中治疗AUD的独特考虑和挑战.
- 在特殊人群中为AUD患者提供临床实践信息和改善治疗结果.
主要方法:
- 进行了全面的文献审查.
- 选了242篇文章,其中57篇被选中进行最终分析.
- 该评论综合了关于特殊人群AUD治疗的最新研究.
主要成果:
- 有四种FDA批准的AUD (MAUD) 药物:迪苏尔菲拉姆,口服纳尔特雷克松,延长释放注射纳尔特雷克松 (XR-NTX) 和阿卡姆普罗沙特.
- 特定的药物具有禁忌和副作用 (例如,肝脏毒性,脏问题,阿片类药物相互作用).
- 建议孕妇/哺乳期患者接受心理社会治疗;XR-NTX可以改善无家可归人口的坚持;青少年可以从药物治疗中受益.
结论:
- 了解和解决AUD特殊人群的独特需求对于有效治疗至关重要.
- 量身定制的治疗策略对于改善AUD患者的健康和福祉至关重要.
- 本综述为优化不同患者群体的AUD护理提供了关键信息.
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