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Updated: Jul 19, 2025

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人性化小鼠模型用于免疫瘤学药物发现

Rajendra Kumari1, Gerold Feuer1, Ludovic Bourré1

  • 1Crown Bioscience Inc., San Diego, California, USA.

Current protocols
|August 8, 2023
PubMed
概括

人性化的小鼠模型改善了对癌症免疫循环的理解,并有助于开发新型免疫疗法. 这些先进的临床前模型对于评估免疫瘤学药物发现中的治疗疗效和安全至关重要.

关键词:
人性化的小鼠.免疫瘤学临床前小鼠模型免疫疗法 免疫疗法来自患者的异种移植.

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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