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Studying Orthodontic Tooth Movement in Mice
Published on: August 2, 2024
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在 ортодонтика元分析中是否适当考虑分析单位?
Samer Mheissen1, Baraa Daraqel2, Khaled Wafaie3
1Syrian Board in Orthodontics, Specialist Orthodontist, Private Practice, Syria, Damascus.
European journal of orthodontics
|August 8, 2023
概括
分析单位 (UoA) 错误在正统牙科元分析中很普遍,只有30%的研究避免了这些错误. 反复测量设计显示正确的UoA的几率更高,与集群设计不同,突出了常见的分析陷.
科学领域:
- 矯正牙科 矯正牙科是一種矯正牙科.
- 生物统计学 生物统计学
- 基于证据的牙科.
背景情况:
- 对分析单元 (UoA) 的准确评估对于元分析至关重要,特别是在复杂的设计中,如集群,分口,重复测量和多个干预组.
- 在UoA中的错误可以显著影响形牙科的元分析结果的有效性和可靠性.
研究的目的:
- 在 ортодонтика元分析中评估分析单位 (UoA).
- 为了确定与UoA错误相关的频率和因素在正统牙科的元分析.
主要方法:
- 系统搜索Cochrane图书馆和PubMed的 ортодонтика系统评论 (SRs) 与2013年至2022年间发表的元分析.
- 包括评估集群试验,交叉试验,多次观察或多个干预组的SR.
- 统计分析包括描述性统计,费舍尔的精确测试,奇平方测试和后勤回归,以确定避免UoA错误的预测因素.
主要成果:
- 包括80个SR;只有30%成功避免了UoA错误.
- 与分口设计相比,重复测量设计的避免UoA错误的几率明显更高 (OR:9.6).
- 集群设计显示,避免UoA错误的几率较低 (OR:0.2),尽管在统计学上并不显著. 科克兰评论和更多的作者与较少的UoA错误有关.
结论:
- 分析单位错误在正统牙科元分析中很常见.
- 虽然一些复杂的设计,如重复测量显示承诺,UoA错误在各种设计中持续存在.
- 期刊类型 (科克兰与非科克兰) 和作者数量影响了对UoA的适当处理.
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