开发和验证实用参数,以建立基于患者报告的结果的前列腺切除术患者的术后症状管理:多中心,前性,观察性队列研究协议
Jie Li1,2, Ting Chen2, Jianguo Gao3
1Department of Urology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
BMJ open
|August 8, 2023
概括
这项研究为前列腺癌 (PC) 患者开发了一个外科手术期间症状量表 (PSS),以优化症状监测和医生干预时间. 该PSS将改善以患者为中心的护理和PC手术后的结果.
科学领域:
- 在瘤学瘤学.
- 手术患者护理手术患者护理
- 健康 结果 研究 研究 结果
背景情况:
- 患者报告的结果对于术后护理至关重要.
- 目前前前列腺癌 (PC) 的症状管理系统缺乏定义的参数.
- 需要一种结构化的方法来监测和管理PC患者的症状.
研究的目的:
- 为PC患者开发一个外科手术期间症状量表 (PSS).
- 为了确定术后症状评估的最佳时间.
- 根据症状的严重程度和变化,建立医生干预标准.
主要方法:
- 在3家医院招募387名PC手术患者.
- 使用中国MD Anderson症状库存 (MDASI) 从手术前到手术后90天的长度数据收集.
- 统计分析包括线性混合模型,以识别显著的症状变化并确定警报值.
主要成果:
- 根据显著的症状波动,将生成一次经手术的症状量表 (PSS).
- 将使用线性混合模型确定适当的后续时间点.
- 医生干预的警报值将使用MDASI衍生的功能状态来确定.
结论:
- 开发的PSS将为PC患者的术后症状监测提供标准化工具.
- 该系统将使及时和适当的医生干预成为可能,增强患者的护理.
- 该研究旨在改善前列腺癌手术后的症状管理和功能状态.
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