刺激的边缘诱导导向导调在上方的colliculus中的方向调整.
Yajie Liang1,2, Rongwen Lu1, Katharine Borges3
1Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, 20148, USA.
Nature communications
|August 8, 2023
概括
鼠标表面上 (sSC) 中的定向和方向柱是依赖于刺激的,不是由电路架构固定的. 边缘刺激诱导导向选择性与sSC神经元中的突出编码相关.
科学领域:
- 神经科学是一个神经科学.
- 视觉处理 视觉处理
- 感官系统 感官系统
背景情况:
- 定向和方向柱在灵长类视觉皮层 (V1) 中得到了很好的记录,但在小鼠中却不存在.
- 最近的研究提出了关于小鼠表面上高层结体 (sSC) 中存在这种柱状组织的相互矛盾的发现.
研究的目的:
- 为了研究小鼠sSC.中的方向和方向柱的存在和刺激依赖性.
- 了解sSC中神经元调特性如何与刺激特征和突出性有关.
主要方法:
- 在清醒的小鼠的sSC上进行了体内成像.
- 刺激包括格子模式来评估神经元反应和地图定向和方向选择性.
- 分析的重点是列的形成和方向选择性和刺激边缘之间的关系.
主要成果:
- 在sSC中存在定向和方向柱的存在高度依赖于刺激.
- 当刺激具有边缘时,观察到柱子,sSC神经元显示方向选择性垂直于边缘方向.
- 边缘诱导的定向选择性与刺激突出在刺激性和抑制性神经元中的编码有关.
结论:
- 鼠标sSC中的神经元调属性不仅仅是由固定电路架构决定的.
- 时空刺激特性,特别是边缘,在sSC中塑造方向选择性和突出性编码方面发挥着至关重要的作用.
更多相关视频
10:05Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia
Published on: January 27, 2018
9.8K
06:46Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity
Published on: March 18, 2019
7.1K
相关概念视频
Equilibrium and Balance
4.8K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
4.8K
The Cochlea
45.2K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
45.2K
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)
390
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
390
Major Somatic Sensory Pathways
1.0K
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
1.0K
Vision
53.6K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
53.6K
Perceiving Loudness, Pitch, and Location
239
The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by...
239
