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Updated: Jul 19, 2025

A Method for Measuring RNA N6-methyladenosine Modifications in Cells and Tissues
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通过m6进行翻译解码的调制 mRNA的修改

Sakshi Jain1, Lukasz Koziej2, Panagiotis Poulis1

  • 1Max Planck Institute for Multidisciplinary Sciences, Göttingen, 37077, Germany.

Nature communications
|August 8, 2023
PubMed
概括

N6-甲基氨酸 (m6A) 修改了mRNA,影响了细菌的翻译. 这种m6A修饰通过破坏复合体的稳定和增加tRNA掉落来阻碍核糖体解码,影响蛋白质合成.

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