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Updated: Jul 19, 2025

Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells
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Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells

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糖原合成酶激酶3通过调节NFAT激活来控制T细胞的耗尽

Yubing Fu1, Jinjia Wang2, Chenfeng Liu3

  • 1State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Science, Xiamen University, Xiamen, 361102, Fujian, China. fuyubingbio@qq.com.

Cellular & molecular immunology
|August 8, 2023
PubMed
概括

糖原合成酶激酶3 (GSK3) 对CD8+T细胞功能至关重要. 抑制GSK3通过促进T细胞耗尽而损害抗瘤免疫力,但抗PD-1疗法可以恢复免疫反应.

关键词:
抗瘤免疫力 抗瘤免疫力这是GSK3的GSK3.抑制性受体的受体T细胞耗尽的情况.病毒感染是一种病毒感染.

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