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Updated: Jul 19, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
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Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

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肠道微生物群对宿主癌症的潜在影响:专注于免疫力,DNA损伤,细胞通路和抗癌疗法

Jiaao Sun1, Feng Chen2, Guangzhen Wu3

  • 1Department of Urology, The First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.

The ISME journal
|August 8, 2023
PubMed
概括

肠道微生物群,人类肠道中的共生细菌,显著影响癌症的发生,进展和治疗. 了解这些微生物对于开发新的抗瘤疗法和个性化医疗方法至关重要.

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Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
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