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体质指数对不同年龄组体外受精结果的影响
Dan Liu1, Li Li1, Ningyu Sun1
1Department of Reproductive Medicine, Shuguang Hospital, affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
BMC women's health
|August 8, 2023
概括
体重指数 (BMI) 显著影响体外受精 (IVF) 的结果,特别是在30-38岁的女性中. 在这个年龄段,正常体重与更高的怀孕和活产率有关,而BMI的影响在年轻或年长的女性中是最小的.
科学领域:
- 生殖医学 生殖医学
- 不孕症研究 不孕症研究
- 肥胖和生育能力问题
背景情况:
- 体重指数 (BMI) 是影响生殖健康的关键因素.
- 了解BMI对体外受精 (IVF) 结果的影响对于优化治疗策略至关重要.
- 以前的研究表明,BMI对生育能力的影响各不相同,因此需要在不同患者队列中进一步调查.
研究的目的:
- 分析身体质量指数 (BMI) 对体外受精 (IVF) 治疗结果的影响.
- 评估BMI类别和关键试管婴儿指标之间的关系,包括怀孕和活产率.
- 调查BMI对试管婴儿成功影响的潜在年龄相关差异.
主要方法:
- 一个追溯的队列研究2311第一次试管婴儿/细胞内精子注射周期从986名妇女.
- 根据BMI,患者被分为体重不足,体重正常,超重和肥胖的组.
- 分析了试管婴儿的结果,并根据患者年龄 (<30,30-38,>38岁) 进一步分层数据.
主要成果:
- 体重不足组在受精卵细胞,切割和可用的胚胎方面表现得更好,Gn剂量和药物治疗日数较低.
- 与超重和肥胖群体相比,正常体重组的30-38岁妇女的植入率,临床怀孕率和活产率显著更高.
- 在30岁以下或38岁以上的女性中,BMI对试管婴儿结果的影响最小.
结论:
- 体重指数显著影响试管婴儿怀孕的结果,特别是在30-38岁的女性中.
- 正常体重与30-38岁年龄段的优异IVF成功率有关.
- 体重指数对试管婴儿结果的影响似乎取决于年龄,对年轻和年长女性的影响不那么明显.
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