奖励处理是否调节或调解了童年逆境和精神病理之间的联系:一项纵向研究
Steven W Kasparek1, Aria Gastón-Panthaki1, Lindsay C Hanford1
1Department of Psychology, Harvard University, Cambridge, MA, USA.
Development and psychopathology
|August 9, 2023
概括
儿童时期的威胁经历,突出奖励敏感性,增加抑郁风险. 然而,高奖励灵敏度可以防止与年轻人剥夺相关的外部化症状.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 精神病学是一个精神病学.
背景情况:
- 童年逆境是精神病理学的重要危险因素.
- 奖励处理变化与逆境和精神病理有关,但它们作为调解者或调节者的作用尚不清楚.
研究的目的:
- 为了调查是否改变行为和神经奖励处理中度或中度的心理病理结果后儿童威胁 (创伤) 和剥夺.
- 研究逆境对青少年奖励敏感性和精神病理学的纵向影响.
主要方法:
- 对10-15岁的青少年进行纵向研究 (N=228在第1波,N=206在第2波).
- 评估了儿童时期的逆境 (威胁和剥夺),精神病理症状,行为奖励敏感性 (货币激励延迟任务) 和休息状态fMRI在第1波.
- 在第二波重新评估精神病理症状.
主要成果:
- 更大的威胁体验与淡的行为奖励灵敏度有关.
- 麻木的奖励灵敏度调解了威胁和随着时间的推移增加的抑郁症症状之间的关联.
- 奖励敏感度缓解了剥夺和外部化症状之间的联系,保护高敏感度的年轻人.
结论:
- 改变的奖励处理,特别是威胁后的敏感性减弱,是将童年逆境与增加的抑郁症联系在一起的机制.
- 对奖励的敏感性可以作为一种保护因素,防止外部化症状,以应对某些年轻人的剥夺.
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