伊朗患有腹腔疾病的儿童的骨矿物质密度
Shokoufeh Ahmadipour1, Mohamad Rostami Nejad2,3, Mojgan Faraji Goodarzi4
1Pediatric Gastroenterologist, Hepatitis Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Gastroenterology and hepatology from bed to bench
|August 9, 2023
概括
患有晚期乳症的儿童通常具有低骨矿物质密度 (BMD),特别是在腰椎. 对代谢性骨疾病的查至关重要,即使在乳病的早期阶段也是如此.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 胃肠病学 胃肠病学
- 内分泌学 在内分泌学.
背景情况:
- 乳病 (CD) 有广泛的肠外表现,包括骨质疏松症,如果忽视,可能是毁灭性的.
- 骨质疏松症在CD中往往未被诊断到严重,对患者和医疗保健系统造成重大负担.
- 伊朗儿科CD患者骨质疏松症的患病率和特征在很大程度上是未知的.
研究的目的:
- 在被诊断患有乳病的儿科患者中评估骨矿物质密度 (BMD).
- 调查伊朗马什II和马什III乳病儿童的低骨密度的流行率和特征.
主要方法:
- 进行了一项横截面研究,对48名被诊断患有Marsh II/III乳病的儿科患者 (18岁以下) 进行了研究.
- 通过双能X射线吸收计收集的数据包括患者人口统计,临床信息,生化参数和骨矿物密度 (BMD).
- 在大腿和腰部区域评估了BMD.
主要成果:
- 腿部区域的患者中有22.9%,腰部区域的患者中有35.4%,观察到低骨密度.
- 没有发现年龄,性别,居住地, Marsh 阶段或无质饮食的坚持与 BMD 之间有显著的相关性.
- 在腰部骨密度和HLA类型DQ8和DQ2/8 (P=0.016) 之间发现了显著的关联.
结论:
- 患有晚期乳病 (Marsh II和III) 的儿童应进行代谢性骨病查.
- 低骨矿物质密度 (BMD) 查也应考虑在Marsh I阶段的乳病患者.
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