阻塞性睡眠呼吸暂停的口服器械治疗:精神病睡眠诊所的一项回顾性研究
Kota Funahashi1, Marina Hirose1, Suguru Kondo2
1Department of Psychiatry, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.
Fujita medical journal
|August 9, 2023
概括
口腔器械 (OA) 有效地治疗阻塞性睡眠呼吸暂停 (OSA),减少嗜睡. 持续率很好,尽管精神病患者的持续率略低.
科学领域:
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
- 医疗器械 医疗器械
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种常见的睡眠障碍.
- 口腔器械 (OA) 是OSA的一种治疗选择.
- 在患有精神病并发症的患者中,OA的有效性和坚持尚未完全理解.
研究的目的:
- 评估口腔器械 (OA) 治疗阻塞性睡眠呼吸暂停 (OSA) 的连续性和有效性.
- 专注于轻度OSA病例和患有精神病并发症的患者.
- 评估OA停止率和临床改善情况.
主要方法:
- 对106名用OAS治疗的OSA患者进行了回顾性分析.
- 卡普兰 - 梅尔对关节炎停止治疗的生存率分析.
- 呼吸暂停-呼吸暂停指数 (AHI) 和爱普沃思睡眠度量表 (ESS) 在OA治疗前后的比较.
- 使用临床全球印象改善 (CGI-I) 尺度进行评估.
主要成果:
- 一年内OA停止率为16.8%,精神病并发症患者 (22.7%) 的更高率趋势.
- 总体CGI-I改善率为37.7%,在患有精神病并发症 (25.0%) 的患者中明显较低.
- 在治疗后,AHI和ESS显著下降,表明治疗疗效跨子组.
结论:
- 口服器具在缓解轻度OSA和患有精神病并发症的患者的嗜睡方面表现出良好的连续性和有效性.
- 在患有精神病并发症的OSA患者中观察到略低的持续率和主观改善率.
- 即使在复杂的患者群体中,OA仍然是OSA的可行的治疗选择.
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