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Updated: Jun 19, 2026

Improving High Viscosity Extrusion of Microcrystals for Time-resolved Serial Femtosecond Crystallography at X-ray Lasers
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混合和挤出:向时间解析蛋白质结晶学注入高粘度样本

Mohammad Vakili1, Huijong Han1, Christina Schmidt1

  • 1European XFEL GmbH, Holzkoppel 4, Schenefeld 22869, Germany.

Journal of applied crystallography
|August 9, 2023
PubMed
概括

一种新方法使用3D打印的微通道来快速混合蛋白质晶体和连接体. 这种技术推进了时间解析晶体学,用于研究蛋白质动态和药物开发.

关键词:
用3D打印的喷嘴进行3D打印.在X射线自由电子激光器.膜蛋白质是一种膜蛋白质.混合和挤出混合和挤出时间分辨率串行晶体学

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相关概念视频

X-ray Diffraction of Biological Samples01:10

X-ray Diffraction of Biological Samples

X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are  scattered by the electron clouds around the sample atoms. The  X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal crystal...