暴露于空气污染物是否会影响疾病的严重程度或慢性鼻炎的结果?
Robert Hagedorn1, Benton Tullis1, Cassidy Nguyen1
1Department of Otolaryngology - Head and Neck Surgery, University of Utah, Salt Lake City, Utah, USA.
International forum of allergy & rhinology
|August 9, 2023
概括
空气污染可能会加剧慢性鼻炎 (CRS) 的严重程度. 较高的二氧化硫和一氧化碳暴露与CRS患者的较差结果相关,这表明空气质量和鼻健康之间存在联系.
科学领域:
- 环境健康 环境健康
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 肺部医学 肺部医学
背景情况:
- 恶劣的空气质量是呼吸道疾病的已知危险因素,包括慢性鼻炎 (CRS).
- 关于空气污染物对CRS疾病严重程度和患者生活质量的具体影响的数据有限.
- 本研究研究了空气污染物暴露与CRS患者的鼻腔特异性和一般生活质量 (QOL) 之间的关联.
研究的目的:
- 评估各种空气污染物对慢性鼻炎 (CRS) 患者的鼻特异性和一般生活质量 (QOL) 措施的影响.
- 在多机构CRS队列中探索空气污染物暴露水平和疾病严重程度结果之间的关系.
主要方法:
- 一项前性,横截面研究招募了486名接受医学治疗或内镜鼻手术 (ESS) 的CRS患者.
- 用SinoNasal Outcome Test (SNOT-22) 和简式6D (SF-6D) 健康效用评分来测量患者报告的结果.
- 根据患者住所邮政编码估计了空气污染物暴露,随后进行了相关性分析.
主要成果:
- 在基线污染物暴露和SNOT-22或SF-6D得分之间没有发现显著的相关性.
- 修订ESS与初级ESS相比,与更高的中位数细颗粒物 (PM2.5) 暴露有关.
- 暴露于二氧化硫和一氧化碳与SNOT-22和SF-6D结果测量相关,表明与疾病严重程度的潜在联系.
结论:
- 空气污染物可能会导致慢性鼻炎 (CRS) 的严重程度.
- 进一步的研究是有必要的,以充分理解空气质量和CRS之间的复杂关系.
- 研究结果表明,环境因素对CRS管理和患者的治疗结果起着作用.
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